NANOM

Published papers in peer-reviewed journals with scientific accomplishments of NANOM project:


1.   Kharlamov AN, Zubarev IV, Shishkina EV, Shur VY. Nanoparticles for treatment of atherosclerosis: Challenges of plasmonic photothermal therapy in translational studies. Future Cardiol. 2018;14(2).   doi:10.2217/fca-2017-0051
2.     Kharlamov AN, Feinstein JA, Cramer JA, Boothroyd JA, Shishkina EV, Shur V. Plasmonic photothermal therapy of atherosclerosis with nanoparticles: Long-term outcomes and safety in NANOM-FIM trial. Future Cardiol. 2017;13(4).
doi:10.2217/fca-2017-0009
3.     Kharlamov AN, Tyurnina AE, Veselova VS, et al. Plasmonics for treatment of atherosclerosis: Results of NANOM-FIM trial. J Nanomedicine Nanotechnol. 2013;4(1). doi:10.4172/2157-7439.1000160
4.     Kharlamov AN, Tyurnina AE, Veselova VS, Kovtun OP, Shur VY, Gabinsky JL. Silica-gold nanoparticles for atheroprotective management of plaques: Results of the NANOM-FIM trial. Nanoscale. 2015;7(17):8003-8015.
doi:10.1039/c5nr01050k
5.     Kharlamov AN. Plasmonic photothermal therapy for atheroregression below Glagov threshold. Future Cardiol. 2013;9(3):405-425.
doi:10.2217/fca.13.16
6.     Kharlamov AN, Gabinsky JL. Plasmonic photothermic and stem cell therapy of atherosclerotic plaque as a novel nanotool for angioplasty and artery
remodeling. Rejuvenation Res. 2012;15(2):222-230. doi:10.1089/rej.2011.1305
7.     Kharlamov AN, Gabinsky JL. Noble metal nanoparticles for plasmonic photothermal therapy of atherosclerosis. In: Technical Proceedings of the 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013. Vol
3. ;
2013:369-372. 

Defeating Atherosclerosis

ABSORB BVS trials

Published papers in peer-reviewed journals with scientific accomplishments of ABSORB project: 

  

1. Kharlamov ANUndiscovered pathology of transient scaffolding remains a driver of failures in clinical trials. World J Cardiol. 2018 Oct 26;10(10):165-186. doi: 10.4330/wjc.v10.i10.165. PubMed PMID: 30386494; PubMed Central PMCID: PMC6205848
2.     Kharlamov AN, Feinstein JA, Cramer JA, Boothroyd JA. What exactly, regression of atherosclerosis or foreign body reaction with hyaline arteriosclerosis, drives transient scaffolding of coronary arteries? A pooled analysis of observational ABSORB studies with a serial multimodality imaging substudy of ABSORB. Int J Cardiol. 2016. doi:10.1016/j.ijcard.2017.05.134
3.     Kharlamov AN. Why do we fail to achieve Glagovian atheroregression in lipid-lowering trials? Interv Cardiol. 2015;7(5):469-482. doi:10.2217/ica.15.37
4.     Kharlamov AN. Scaffold thrombosis: Exaggerated illusion, or when statistics rules. Int J Cardiol. 2016;209:206-209. doi:10.1016/j.ijcard.2016.02.054
5.     Kharlamov AN. Can we adapt histological injury score for optical coherence tomography of coronaries? Int J Cardiol. 2013;168(4):4322-4324. doi:10.1016/j.ijcard.2013.04.168
6.     Muramatsu T, Onuma Y, Zhang Y-J, ... Kharlamov ANet al. Progress in treatment by percutaneous coronary intervention: The stent of the future | Avances en el tratamiento mediante intervención coronaria percutánea: el stent del futuro. Rev Esp Cardiol. 2013;66(6):483-496. doi:10.1016/j.recesp.2012.12.009
7.     Muramatsu T, Onuma Y, Zhang Y-J, ... Kharlamov ANet al. Progress in treatment by percutaneous coronary intervention: the stent of the future. Rev Esp Cardiol (Engl Ed). 2013;66(6):483-496. doi:10.1016/j.rec.2012.12.009
8.     Kharlamov AN. Bioresorbable scaffolds for atheroregression: Understanding of transient scaffolding. Curr Cardiol Rev. 2016;12(1):66-82.
9.     Kharlamov AN, Duckers HJ, Van Beusekom HMM, Smits PC, Perin EC, Serruys PW. Do we have a future with transcatheter adventitial delivery of stem cells? Int J Cardiol. 2013;165(2):217-221. doi:10.1016/j.ijcard.2012.11.063
10.     Lemos PA, Farooq V, Takimura CK, ... Kharlamov AN, et al. Emerging technologies: Polymer-free phospholipid encapsulated sirolimus nanocarriers for the controlled release of drug from a stent-plus-balloon or a stand-alone balloon catheter. EuroIntervention. 2013;9(1):146-156. doi:10.4244/EIJV9I1A21
11.     Kharlamov AN. Phenomenon of elongated struts: Is optical coherence tomography accurate enough to analyze scaffold area? Int J Cardiol. 2013;168(4):4280-4284. doi:10.1016/j.ijcard.2013.04.201
12.     Onuma Y, Muramatsu T, Kharlamov A, Serruys PW. Freeing the vessel from metallic cage: What can we achieve with bioresorbable vascular scaffolds? Cardiovasc Interv Ther. 2012;27(3):141-154. doi
:10.1007/s12928-012-0101-8

FIGURES FROM PAPERS

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2014-06-14-18-25-39--1498101714

POSTERS

CRT 2016
CRT 2016
CRT 2016
ESC 2018
ESC 2015
SCAI 2017
TCT 2016
TCT 2016
NN 2017
SCAI 2017
ESC 2015
ACC 2018
CIT 2017
EuroPCR 2017
CRT 2016

GEOGRAPHY OF RESEARCH COLLABORATION

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ACKNOWLEDGEMENTS

Prof. Jan L. Gabinsky

Ural Institute of Cardiology, Yekaterinburg, Russia

For mentorship of professional development in general cardiology and public health in 1996-2013

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Prof. Patrick W.J.C. Serruys

National Heart & Lung Institute, Imperial College, London, U.K.

For mentorship in interventional cardiology in 2011-2013

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Center for Modern Nanotechnologies, Ural Federal University, Yekaterinburg, Russia

For mentorship in nanotechnology

in 2011-2018

Prof. Vladimir Ya. Shur
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Board of Directors of Radboud UMC, Radboud University, Nijmegen, The Netherlands

For mentorship in translational cardiovascular biomedicine

in 2009-2010

Prof. Paul A.B.M. Smits
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Andrews Memorial Hospital, Kingston, Jamaica

For professional collaboration, sponsorship, and strong endorsement of FESC, and FACC applications in 2018-2019

Dr Sandra Williams-Phillips
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University of Erlangen, Germany

For professional synergy, and support of FESC, and FACC recognitions

in 2018-2019

Prof. Stephan Achenbach
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University College London (UCL), London, the United Kingdom

For support of FESC application

in 2018

Prof. Bryan Williams
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Charles University in Prague, Prague (CUNI), Czech Republic

For essential backing of FESC application in 2018

Prof. Zuzana Motovska

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